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Department of Chemical & Biological Sciences

Head of Department

Dr. Amit Kumar Paul
Ph.D, IACS, University of Calcutta

E-mail:
hod.cy@nitm.ac.in

Ph.D

Mr. Sourav Das Research Scholar

  • B. Sc. Chemistry from St. Edmund’s College (2013)
  • M. Sc. Chemistry from NEHU, Shillong (2015).

souravdas@nitm.ac.in souravdas1891@gmail.com
+919774282449
Full Time/Part Time Scholar: Full-Time
Professional Membership : NA

Highest Degree with specialization(Name of Institute):

  • M.Sc Chemistry (North Eastern Hill University)

Academic Honors & Awards:

  • SLET-2019
  • CSIR UGC NET-LS, AIR-74 (June 2020)
  • Ranked 2nd (position) in M.Sc. (Chemistry), NEHU 2015.
  • Best poster award at the National Seminar on Recent Developments in Chemistry, July 12 -13, St. Mary’s college, Shillong, 2017.
  • Best poster award at the National Conference on Recent Advances in Chemistry, October 14 -15, NIT Meghalaya, Shillong, 2019.
  • Received the Institute Best Research Award, awarded by the National Institute of Technology Meghalaya at the Research Conclave, 2020.
  • Indian Chemical Society Research Excellence Award for oral Presentation in international seminar on “Recent Advances in Chemistry & Material Sciences (2020)” held in the month of August 2020.

Research Area:

  • Protein Chemistry
  • Protein-Ligand interaction
  • Protein fibrillation and glycation
  • Biocompatible nanoparticles
  • Computational biophysics

Seminar/Conference Attended:

  • Annual Symposium of the Indian Biophysical Society at IISER Mohali, March 23-25, 2017.
  • National Seminar on Recent Developments in Chemistry, July 12 -13, St. Mary’s college, Shillong, 2017.
  • Recent Trends in Chemical Sciences (RTCS) October 12-13, NIT Meghalaya, 2017.
  • National Workshop On Fluorescence And Raman Spectroscopy FCS 2017 December 17-21, IIT Guwahati, 2017.
  • National Seminar on Contemporary Challenges in Chemistry, November 20-21, NEHU, Shillong, 2018.
  • Frontiers in Chemical Sciences (FICS), December 6- 8, 2018, IIT Guwahati, 2018.
  • National Conference on Recent Advances in Chemistry (RAC2019), October 14 -15, NIT Meghalaya, Shillong, 2019.
  • National Symposium on Recent Trends in Chemistry (RTC-19), NEHU, Shillong from 31st Oct till 01st Nov, 2019.
  • International seminar on “Recent Advances in Chemistry & Material Sciences (2020)” held in the month of August 2020 (online mode).
  • Online workshop on Powder X-Ray diffraction techniques and its applications, NECBH, IIT Guwahati, Assam held on 20th and 21st January 2021.

Publications:

  • Das, S.; Sarmah, S.; Hazarika, Z.; Rohman, M. A.; Sarkhel, P.; Jha, A. N.; Roy, A. S. Targeting the Heme Protein Hemoglobin by (-)-Epigallocatechin Gallate and the Study of Polyphenol-Protein Association Using Multi-Spectroscopic and Molecular Docking Methods. Phys. Chem. Chem. Phys. 2020, 22, 2212-2228. https://doi.org/10.1039/C9CP05301H.
  • Das, S.; Sarmah, S.; Singha Roy, A. Monitoring Fluorescence Emission Behaviors of Dietary Polyphenols in a Serum Albumin Environment. New J. Chem. 2020,44, 299-302. https://doi.org/10.1039/C9NJ03938D.
  • Das, S.; Pahari, S.; Sarmah, S.; Rohman, M. A.; Paul, D.; Jana, M.; Singha Roy, A. Lysozyme-Luteolin Binding: Molecular Insights into the Complexation Process and the Inhibitory Effects of Luteolin towards Protein Modification. Phys. Chem. Chem. Phys. 2019, 21, 12649–12666. https://doi.org/10.1039/c9cp01128e.
  • Das, S.; Khanikar, P.; Hazarika, Z.; Rohman, A.; Uzir, A.; Jha, A. N.; Singha Roy, A. Deciphering the Interaction of 5 , 7-Dihydroxyflavone with Hen-Egg-White Lysozyme through Multispectroscopic and Molecular Dynamics Simulation Approaches. ChemistrySelect 2018, 3 (17), 4911–4922. https://doi.org/10.1002/slct.201800280.
  • Das, S.; Bora, N.; Rohman, M. A.; Sharma, R.; Jha, A. N.; Singha Roy, A. Molecular Recognition of Bio-Active Flavonoids Quercetin and Rutin by Bovine Hemoglobin: An Overview of the Binding Mechanism, Thermodynamics and Structural Aspects through Multi-Spectroscopic and Molecular Dynamics Simulation Studies. Phys. Chem. Chem. Phys. 2018, 20 (33), 21668–21684. https://doi.org/10.1039/C8CP02760A.
  • Das, S.; Rohman, M. A.; Singha Roy, A. Exploring the Non-Covalent Binding Behaviours of 7-Hydroxyflavone and 3-Hydroxyflavone with Hen Egg White Lysozyme: Multi-Spectroscopic and Molecular Docking Perspectives. J. Photochem. Photobiol. B Biol. 2018, 180, 25–38. https://doi.org/10.1016/j.jphotobiol.2018.01.021.
  • Das, S.; Karn, A.; Sarmah, R.; Rohman, M. A.; Koley, S.; Ghosh, P.; Singha Roy, A. Characterization of Non-Covalent Binding of 6-Hydroxyflavone and 5,7-Dihydroxyflavone with Bovine Hemoglobin: Multi-Spectroscopic and Molecular Docking Analyses. J. Photochem. Photobiol. B Biol. 2017, 178, 40–52. https://doi.org/https://doi.org/10.1016/j.jphotobiol.2017.10.021.
  • Das, S.; Santra, S.; Rohman, M. A.; Ray, M.; Jana, M.; Singha Roy, A. An Insight into the Binding of 6-Hydroxyflavone with Hen Egg White Lysozyme: A Combined Approach of Multi-Spectroscopic and Computational Studies. J. Biomol. Struct. Dyn. 2018, 1–16. https://doi.org/10.1080/07391102.2018.1535451.
  • Das, S.; Ghosh, P.; Koley, S.; Singha Roy, A. Binding of Naringin and Naringenin with Hen Egg White Lysozyme: A Spectroscopic Investigation and Molecular Docking Study. Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 2018, 192, 211–221.https://doi.org/10.1016/j.saa.2017.11.015.
  • Sarmah, S.; Pahari, S.; Das, S.; Belwal, V. K.; Jana*, M.; Singha Roy*, A. Non-Enzymatic Glycation of Human Serum Albumin Modulates Its Binding Efficacy towards Bioactive Flavonoid Chrysin: A Detailed Study Using Multi-Spectroscopic and Computational Methods. J. Biomol. Struct. Dyn. 2020, 1–24.https://doi.org/10.1080/07391102.2019.1711196.
  • Das, S., Sarmah, Lyndem, S, Singha Roy,* A, An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study, J. Biomol. Struct. Dyn. 2020.
  • Das, S.; Hazarika, Z.; Sarmah, S.; Rohman, M.A.; Paul, D.; Jha, A.N; Singha Roy, A.*, Exploring the interaction of bioactive kaempferol with serum albumin, lysozyme and hemoglobin: A biophysical investigation using multi-spectroscopic, docking and molecular dynamics simulation studies. J. Photochem. Photobiol. B Biol. 2020
  • Sarmah, S.,Das, S., Singha Roy,* A, Protective actions of bioactive flavonoids chrysin and luteolin on the glyoxal induced formation of advanced glycation end products and aggregation of human serum albumin: in vitro and molecular docking analysis, Int.l J. of Biological Macromolecules. 165, 2020, 2275-2285.
  • Das, S., Langbang, L., Haque, M., Belwal, V. K., Aguan, K., Singha Roy, A. Biocompatible silver nanoparticles: An investigation into their protein binding efficacies, anti-bacterial effects and cell cytotoxicity studies. Journal of Pharmaceutical Analysis (just accepted)
  • Singha Roy, A., Sarmah, S, Das, S., Effects of Glycation on Serum albumin, in A Closer Look at Glycation, Nova Science publishers, 2021, pp 21-78. ISBN: 978-1-53619-176-9.

Any other remarkable experiences

  • 2017-2019: Physical Chemistry laboratory classes as TA duty
  • Spring 2020: Environmental Science (CY102) classes of B.Tech (Semester II) as TA duty