Department of Chemical & Biological Science

Head of Department

Dr. Amit Kumar Paul
Ph.D, IACS, University of Calcutta

E-mail:
hod.cy@nitm.ac.in

Ph.D

Ms. Sona Lyndem Research Scholar

  • B. Sc. Chemistry from St. Anthony’s College, NEHU (2008-2011),
  • M. Sc. Life Sciences from JNU, New Delhi (2011-2013).

sonalyndem@gmail.com
+918794352765
Full Time/Part Time Scholar: Part-Time

Highest Degree with specialization(Name of Institute):

  • M.Sc Life Sciences (JNU, New Delhi)

Academic Honors & Awards:

  1. Gold medalist Chemistry (B.Sc) North Eastern Hill University
  2. GATE- 2013
  3. CSIR-NET 2012
  4. Best poster award on the topic “A comprehensive in vitro exploration into the interaction mechanism of coumarin derivatives with bovine hemoglobin: Spectroscopic and computational methods” presented in International Symposium on “Emerging trends in Chemical Sciences” organised in North Eastern Hill University from 2nd – 4th March 2023

Research Area:

  • Protein-ligand interaction
  • Protein fibrillation
  • Antimicrobial studies
  • Silver nanoparticles

Seminar/Conference Attended:

  1. One day Sensitization workshop on “ Technological Empowerment of women through the SoRF Scheme of DST in collaboration with NASI” organized by National Academy of Sciences, India (NASI) NER Local Chapter at North Eastern Hill University, Shillong, on 30th June, 2014.
  2. Faculty Development Programme, “Research Capability Enhancement” organized by the Research Cell, St. Anthony’s College, Shillong under the aegis of IQAC, St. Anthony’s College, Shillong on the 23rd August, 2014.
  3. DBT sponsored workshop on “ Capacity building in Effective Management of Intellectual Property Rights (IPRs) in Biotechnology by Universities and Research Institutes in Meghalaya” organized by BCIL, New Delhi at St. Anthony’s College, Shillong on the 22nd and 23rd September, 2014.
  4. EMBO Workshop on “Upstream and downstream of Hox genes” held at Centre for Cellular and Molecular Biology, Hyderabad, India on 14th-17th December 2014.
  5. Guest Lectures on “Biochemical and Genetic Characterization of Young Onset Diabetes Mellitus” and “The Potential of Herbs in the Management of Type 2 Diabetes Mellitus” organized by the Deptt. of Biotechnology, St. Anthony’s College on 16th March, 2015.
  6. Short term course on “Drug Design” under Continuing Education Programme held in Indian Institute of Technology, New Delhi on 21st–23rd September 2015.
  7. Training Workshop on “R software and Perl” organized by the DBT-BIF, St. Anthony’s College from 28th March–2nd April, 2016.
  8. “Capacity Building Workshop” organized by the Centre for Education Beyond Curriculum (CEDBEC), Christ University, Bengaluru from the 20th – 25th June, 2016.
  9. International Conference on “Recent Trends in Agriculture, Veterinary & Life Sciences – 2017” organized by Carmel College of Arts, Science & Commerce for Women, Goa and International Multidisciplinary Research Foundation from 2nd- 4th February, 2017.
  10. International Seminar on “Understanding Water Crisis: The Way Forward” organized by Synod College, Shillong, in collaboration with P.A. Sangma Foundation and Meghalaya Basin Development Authority held on 6th-7th June, 2019.
  11. National Seminar on ‘Recent Advancements in Science and Technology” organized by Union Christian College, through the Science Society in collaboration with North Eastern Space Application Centre (NESAC), Umiam, P.A. Sangma Foundation and College of Post Graduate Studies in Agricultural Sciences, Umiam held on 12th-14th June 2019.
  12. UGC-Sponsored Special Summer School in “Basic Sciences and Technology” organized by Human Resource Development Centre, North Eastern Hill University, held on 8th-21st July 2019.
  13. Orientation Programme on Student Engagement and Neural Mechanism of Learning” organized by St. Anthony’s College on 7th March 2020
  14. 4-Week Induction/Orientation Programme for “Faculty in Universities/Colleges/Institutes of Higher Education” organized by Ramanujan College University of Delhi from 11th February to 13th March 2021
  15. Seminar on “New species discovery in Meghalaya and the importance of conservation” organized by St. Anthony’s College on 22nd May 2021
  16. Training cum Workshop on the “Use of KOHA Software in Libraries” organized by North Eastern Hill University on 16th – 17th September 2021
  17. Refresher course on Managing Online Classes and Co-creating MOOCs organized by Ramanujan College, New Delhi on 7th- 21st March 2022
  18. International students workshop in Timisoara on “Education” organized by Polytechnic University in Romania from 25th July- 2nd August 2022
  19. International students festival in Trondheim on “Research in science” organized by Norwegian Institute of Science and Technology, Trondheim, Norway from 9th – 19th February 2023
  20. International Symposium on “Emerging trends in Chemical Sciences” organized by North Eastern Hill University on 2nd – 4th March 2023

Publications:

  1. Lyndem, S., Hazarika, U, Bhatta, A., Prakash, V., Jha, A., Singha Roy, A. In-vitro interactions of esculin and esculetin with bovine hemoglobin alter its structure and inhibit aggregation: Insights from spectroscopic and computational studies. NJC (2023) https://doi.org/10.1039/D3NJ02273K
  2. Lyndem, S., Gazi, R., Belwal, V.K., Bhatta, A., Jana, M., Singha Roy, A. Binding of bioactive esculin and esculetin with hen egg white lysozyme: Spectroscopic and computational methods to comprehensively elucidate the binding affinities, interacting forces, and conformational alterations at molecular level. J. Mol. Liq. 360, 119423 (2022).
  3. Lyndem, S., Hazarkia, U., Athul, P., Bhatta, A., Prakash, V., Jha, A., Singha Roy, A. A comprehensive in vitro exploration into the interaction mechanism of coumarin derivatives with bovine hemoglobin: Spectroscopic and computational methods. J. Photochem. Photobiol. A Chem. 436, 114425 (2023).
  4. Haque, M., Konthoujam, I., Lyndem, S., Koley, S., Aguan, K., Singha Roy, A.. Formation of ZnS quantum dots using green tea extract: applications to protein binding, bio-sensing, anti-bacterial and cell cytotoxicity studies. J. Mater. Chem. B 11, 1998–2015 (2023).
  5. Haque, M., Lyndem, S., Singha Roy, A. Interaction properties of biosynthesized cadmium sulphide quantum dots with human serum albumin: further investigation of antibacterial activities and sensing applications. Luminescence 37, 837–853 (2022).
  6. Baruah, K., Konthoujam, I., Lyndem, S., Aguan, K., Singha Roy, A. Complexation of turmeric and curcumin mediated silver nanoparticles with human serum albumin: Further investigation into the protein-corona formation, anti-bacterial effects and cell cytotoxicity studies. Spectrochim. Acta Part A Mol. Biomol. Spectrosc. 294, 122540 (2023).
  7. Lyndem, S., Gazi, R., Jana, M., Belwal, V.K., Singha Roy, A. Molecular recognition of two bioactive coumarin derivatives 7-hydroxycoumarin and 4-methyl-7-hydroxycoumarin by hen egg white lysozyme: Exploring the binding mechanism, thermodynamic parameters and structural changes using multispectroscopic and computational approaches. J. Biomol. Struct. Dyn. 40, 13872–13888 (2022).
  8. Sarmah, S., Dhurua, S., Belwal, V.K., Lyndem, S., Jana, M., Singha Roy, A. Combined spectroscopic and computational approaches for the recognition of bioactive flavonoid 6-hydroxyflavone by human serum albumin: Effects of non-enzymatic glycation in the binding. J. Mol. Liq. 346, 118288 (2022).
  9. Das, S., Sarmah, S., Lyndem, S., Singha Roy, A. An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study. J. Biomol. Struct. Dyn. 39, 3347–3357 (2021).
  10. Lyndem, S. The state of the education system at the time of COVID-19 pandemic and its reprecussions. Political Anvil. Dept of Political Science. Synod College (2020)
  11. Lyndem, S. and Syiem, J.N. (2016). “A comparative study Antibacterial properties of traditional oils produced from Umwai village, Mawlai town and Lyngkyrdem village of the state of Meghalaya”, Biological Forum- An International Journal, Vol. 8(1), pp. 221-225, ISSN 0975-1130.
  12. Lyndem, S., Sarmah, S., Das, S. & Singha Roy, A. Chapter 6 - Coumarin derivatives: biomedicinal properties and interactions with carrier proteins. in (ed. Atta-ur-Rahman, B. T.-S. in N. P. C.) vol. 73 173–220 (Elsevier, 2022).

Teaching Experience:

 Assistant Professor, Department of Biotechnology, St. Anthony’s College, Shillong (2014-Present)